Peter Welge, Dipl.-Biol.

(equivalent to MSc. biol.)

Research Scientist

Centre of Toxicology


  • Studies in Biology at the Ruhr-University Bochum, Germany; Diploma (equivalent to MSc) in 1993
  • Participation in the postgraduate education programme "Fachtoxikologe" of the DGPT


The topics of my research are in the field of genotoxicity caused by hazardous substances, chemical carcinogenesis and genotoxicological-epidemiological studies in occupational and environmental risk assessment. The overall goal is to protect persons from work- or environment-related diseases. Apart from genotoxicity, my focus is also on evaluation of toxic effects in animal studies and on the impact of bioavailability of substances in risk assessment.


Institutional Animal Welfare Officer for the experimental animal unit of the IPA and Bergmannsheil University Clinic.

Selected Publications

  • Bauer AK, Velmurugan K, Plöttner S, Siegrist KJ, Romo D, Welge P, Brüning T, Xiong KN, Käfferlein HU. Environmentally prevalent polycyclic aromatic hydrocarbons can elicit co-carcinogenic properties in an in vitro murine lung epithelial cell model. Arch Toxicol. 2018 Mar;92(3):1311-1322
  • Lotz A, Pesch B, Dettbarn G, Raulf M, Welge P, Rihs HP, Breuer D, Gabriel S, Hahn JU, Brüning T, Seidel A. Metabolites of the PAH diol epoxide pathway and other urinary biomarkers of phenanthrene and pyrene in workers with and without exposure to bitumen fumes. Int Arch Occup Environ Health. 2016 Nov;89(8):1251-1267
  • Pesch B, Lotz A, Koch HM, Marczynski B, Casjens S, Käfferlein HU, Welge P, Lehnert M, Heinze E, Van Gelder R, Hahn JU, Behrens T, Raulf M, Hartwig A, Weiß T, Brüning T. Oxidatively damaged guanosine in white blood cells and in urine of welders: associations with exposure to welding fumes and body iron stores. Arch Toxicol. 2015 Aug;89(8):1257-69
  • Kendzia B, Pesch B, Marczynski B, Lotz A, Welge P, Rihs HP, Brüning T, Raulf-Heimsoth M. Pre- and postshift levels of inflammatory biomarkers and DNA damage in non-bitumen-exposed construction workers-subpopulation of the German Human Bitumen Study. J Toxicol Environ Health A. 2012;75(8-10):533-43
  • Welge P, Marczynski B, Raulf-Heimsoth M, Spickenheuer A, Kendzia B, Heinze E, Angerer J, Käfferlein HU, Pesch B, Brüning T. Assessment of micronuclei in lymphocytes from workers exposed to vapours and aerosols of bitumen. Arch Toxicol. 2011 Jun;85 Suppl 1: S65-71
  • Marczynski B, Raulf-Heimsoth M, Spickenheuer A, Mensing T, Welge P, Förster K, Angerer J, Pesch B, Bramer R, Käfferlein HU, Breuer D, Hahn JU, Brüning T. Ambient and biological monitoring of exposure and genotoxic effects in mastic asphalt workers exposed to fumes of bitumen. J Occup Environ Hyg. 2007;4 Suppl 1:127-36.
  • Wittsiepe J, Erlenkämper B, Welge P, Hack A, Wilhelm M. Bioavailability of PCDD/F from contaminated soil in young Goettingen minipigs. Chemosphere. 2007;67(9):S355-64.
  • Marschner B, Welge P, Hack A, Wittsiepe J, Wilhelm M. Comparison of soil Pb in vitro bioaccessibility and in vivo bioavailability with Pb pools from a sequential soil extraction. Environ Sci Technol. 2006;40(8):2812-8.
  • Welge P, van Kampen V, Mensing T, Brüning T. Beryllium and Beryllium Compounds: 15. Toxicology and Occupational Health. In: Ullmann's Encyclopedia of Industrial Chemistry, 7th edition, Wiley-VCH Verlag, Weinheim 2005
  • Roos PH, Tschirbs S, Hack A, Welge P, Wilhelm M. Different mechanisms of handling ingested polycyclic aromatic hydrocarbons in mammalian species: organ-specific response patterns of CYP1A1-induction after oral intake of PAH-contaminated soils. Xenobiotica. 2004;34(9):781-95.
  • Roos PH, Tschirbs S, Pfeifer F, Welge P, Hack A, Wilhelm M, Bolt HM. Risk potentials for humans of original and remediated PAH-contaminated soils: application of biomarkers of effect. Toxicology. 2004;205(3):181-94./li>
  • Roos PH, Tschirbs S, Hack A, Welge P, Wilhelm M. Different organ-specific responses of CYP1A1-induction in minipigs and rats after oral intake of PAH-contaminated soil particles. In: Döhmer J, Fleck C, Keppler D, Müller D, Ullrich KJ (eds.): Molecular investigation of metabolism and transport of drugs - From animal to human tissue (pp 305-307). Stuttgart: Wiss. Verl.Ges., 2003 (Nova Acta Leopoldina N.F., Vol. 87, No. 329)
  • Roos PH, Tschirbs S, Welge P, Hack A, Theegarten D, Mogilevski G, Wilhelm M. Induction of cytochrome P450 1A1 in multiple organs of minipigs after oral exposure to soils contaminated with polycyclic aromatic hydrocarbons (PAH). Arch Toxicol. 2002;76(5-6):326-34
  • Mensing T, Welge P, Voss B, Fels LM, Fricke HH, Brüning T, Wilhelm M. Renal toxicity after chronic inhalation exposure of rats to trichloroethylene. Toxicol Lett. 2002;128(1-3):243-7./li>


German, English